In March 2002, Simran was signed up to endorse Fanta, the tangy orange-flavoured drink from Coca-Cola. According to a company spokesperson, “Film stars cut across various segments to establish a direct connect with the brand.” The ad was conceived by the Lowe and directed by filmmaker Latha Menon. In the same year, Jyoti Labs launched Jeeva soap with Simran to endorse the brand along with the advertisements. On 4 June 2008, PepsiCo announced Simran as the new brand ambassador for Kurkure for their brand in the South Indian market. Simran was chosen as the brand ambassador for the low-calorie sugar substitute Sugar Free Gold by Cadila Healthcare. She is also connected with General Mills India for Pillsbury Atta & has appeared in several TV commercials. She has recently signed with Dabur India for Dabur Sanitizer. Few of her endorsements are Enfagrow A+ with her Younger Son, Pothys silk sarees by Pothys, Arun ice creams, Nac, Chinni Masala by cavinkare, lion dates & Manna health care.